PHARMACEUTICAL IP

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  • Our Offering
    • Due diligence
    • Established pharma
    • Evolve AI
    • Fractional IP
    • International IP counsel
    • Investors
    • Oppositions and appeals
    • Start-ups
  • Fractional IP
  • Evolve AI
  • Sectors
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    • Biotechnology
    • Biologics
    • Cell & gene therapy
    • AI drug discovery
    • Chemistry
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Evolve AI

We are pharma patent attorneys who build and use our own AI agents

We develop our own AI tools and have incorporated them throughout our practice. The thinking and expertise is ours. We use AI to do more, more quickly.

We started building our own AI agents because the legal AI products we tried were not suited for pharma and biotech IP work. We have developed our own AI tools that we use ourselves, day to day, and which solve problems that we and our clients actually have. 

Our AI agents

Albert (validity) Popper (prosecution) Darwin (drafting) Cassandra (due diligence) Gilbert (quality) Franklin (invention spotting) Ammonites (portfolio visualisation)

8+

AI agents, written by our own attorneys

30+

interconnected skills & modules

12+

months of testing by senior attorneys before anything touched client work

100%

of Evolve attorneys, paralegals and implementors using AI

How our AI agents help our clients

Our AI agents help us provide more value for our clients.

We can look at more

Basis checks, data mapping, office actions, portfolio reviews. Our attorneys do all of this themselves, as they always have. The difference is that our AI agents are able to efficiently gather the information for attorney review. We can look at more, in more depth, and earlier in the process.

Senior time goes on the judgement calls

The tools collect and prepare. Our patent attorneys still make the decisions: what does the data supports, how to strategically amend or argue against an objection, and how to align the IP and commercial strategy.

Problems surface early, when you can still deal with them

Our AI tools are designed to help us provide advice based on deep-analysis early on, when it can still be acted on. This means before full due diligence, opposition or litigation proceedings. 

Why we built our own AI

We don't use an off-the-shelf AI IP software solution. We strongly believe that effective use of AI in the patent industry requires keeping the patent attorney in the driving seat and not out-sourcing our expertise to non-legally qualified software engineers.

Our AI tools use frontier models, are built by our own attorneys and implementors, and are pharma/biotech specific. 

Off-the-shelf tools are not suitable for the work we do

Every AI patent tool on the market runs on models from the frontier LLM labs. We believe that putting someone else’s software between the attorney and the model adds cost and restriction, and very little else.

Learn to drive it yourself

An off-the-shelf tool ties you to the developer’s idea of how patent work should go, and it stops your attorneys picking up the one skill that now matters, which is instructing the model well. We write our own instructions and workflows, and the case law and drafting rules inside them are ours.

Work from the documents, not from memory

Ask an LLM to argue from what it happens to remember and it will make things up, including citations and data. Our tools only see what the attorney gives them: the specification, the prior art, the prosecution history, the lead compound or sequence, the strategy and our instructions.

Automation is not AI

A sequence listing has to match the data exactly, and a language model is the wrong tool for that. So sequence listings, compound extraction and Markush interpretation are done in code. We keep the language models for work that use language.

Fewer layers, fewer things to go wrong

Our duty of confidentiality applies to AI exactly as it does to email or the cloud. We build directly on the frontier labs under enterprise terms. Nothing is kept, nothing is used for training, and there is no third party in the middle whose arrangements we would also have to vet.

Keep it interactive, and keep it current

The patent attorney steers each step and can see the working, so there is no black box behind the advice. We test every tool against the latest decisions before we rely on it, and when the law or the model moves we update it ourselves, usually within days, rather than waiting on a vendor.

Built by the attorneys who use them

Most legal AI is written by software companies trying to work out what lawyers do. Ours is written by pharma patent attorneys who have done the in-house job, and who use the tools on live cases every day.

We proudly consider ourselves experts in pharma IP: 

  • We have run global patent strategy for on-market products and IP diligence on multi-billion-dollar deals, so the tools are aimed at what matters in a portfolio.
  • We are case law experts and industry thought-leaders. We edit the CIPA Guide to the Patents Acts and write for IPKat, and are regular guests on industry podcasts. The knowledge inside our tools is current and properly understood.
  • We use every tool on our own cases, so everyone at Evolve knows how they behave and suggest improvements.

 

Dan Mulryan, European Patent Attorney

“As a new member of the team who has not previously used AI systems in my day-to-day work, I have been thoroughly impressed by the sophistication of Evolve’s AI tools. They are not just useful for sense-checking finished pieces of work but also help streamline the preparation of my work.”

Claudia Greaves, CIPA Advanced Patent Paralegal

“Using the AI tools has made me much more efficient, along with reassuring me that the judgement calls I am making are right. I love being able to see a bottleneck or an area that can be improved in our workflows and work with the AI to find a solution.”

Our proprietary AI agents

Popper

Prosecution. Translates and summarises the office action and sets up the groundwork for our response.

Albert

Validity and opposition. Novelty, inventive step, support, added matter, priority and data strength, laid out for us to review.

Darwin

Drafting. Claim sets, amendments, specification sections and ST.26 sequence listings, prepared to our instructions.

Mendel

Amendments. Claim amendments and basis tables for EP, US and other jurisdictions.

Gilbert

Quality. A second read of specifications, sequences, compounds and responses, with each issue graded.

Franklin

Invention spotting. Finds inventions and disclosure risks in draft publications and competitor filings.

Cassandra

Due diligence. Gathers and organises the evidence on coverage, validity, ownership and contract terms.

Ammonite Chart

Patent estate and loss-of-exclusivity charts that show how long the protection runs.

Contact us

Albert: Validity, oppositions and competitive intelligence

Albert sets out a patent’s data, construes the claims and finds the weak points so that we can get to the analysis quickly.

In pharma, validity nearly always comes down to the data. Albert is a set of modules, one for each question we tend to ask of a patent, whether it belongs to a competitor, a licensing target or one of our own clients. It prepares:

  • Data: each embodiment matched to its effect, the experiments behind it and the claims it supports, with a score for how good the evidence is
  • Basis, support, novelty, inventive step and priority: claim by claim, against the application as filed, the data and the prior art
  • Sequences and Markush formulae: lead sequences checked, generic formulae drawn out, expanded or compared with a real compound
  • Construe: each claim term read against the specification

We use Albert for competitive intelligence, freedom to operate, oppositions and diligence. Albert allows us to gets us to a strategic view quickly, and we go deeper only where a particular risk warrants it. More on Albert and Albert Construe.

In practice

A competitor’s 300-page patent arrives. Albert pulls out each embodiment with its data and its claims. We then do the analysis we would always have done, only sooner: is this patent a real threat, where is it weak, and is a full FTO opinion worth the money.

Popper: Global patent prosecution

Popper puts the office action, the file history, your strategy and the relevant case law in front of the attorney on the day it arrives.

The arguments that persuade the EPO are not the ones that work at the USPTO or the JPO. Popper carries a knowledge bank we wrote ourselves on the evidence needed for clinical-use inventions, sequence claims for biologics, comparative data, and the habits of each office. When an office action comes in, Popper prepares:

  • A translation and a summary, for triage and for your report
  • The cited sequences or compounds, extracted
  • The objections set against the prosecution history and your strategy
  • A first pass at the rebuttal and amendments, on current case law, for the attorney to work from

The attorney then decides whether to push on or slow down, narrow or broaden, and how to keep the family consistent across countries. The name comes from Sir Karl Popper, who insisted that a scientific theory must be falsifiable. It seemed a good fit for an agent whose job is science-backed rebuttals.

In practice

An office action arrives in Japanese. Before the attorney has opened it, Popper has translated and summarised it, pulled out the cited sequences, and set the objections against the file history, your strategy and the Japanese case law. The attorney starts with the whole picture in front of them.

Darwin: Patent drafting

Darwin drafts the claims, the specification and the sequence listing alongside the attorney, one decision at a time.

Drafting a pharma application means working out what the data will support before you decide what to claim. Darwin is built around that order of events, for small molecules, biologics and cell and gene therapy. It prepares:

  • Claims: from the data, with the attorney choosing the claim format and the drug definition at each step
  • Claim iteration: amendments added to an existing set without disturbing it, and the numbering tracked
  • Specification: each section written from the claims and the data, with the figures pulled out and labelled
  • Sequence listing: a compliant ST.26 file produced in code rather than by a language model, because the listing has to match the data exactly

Gilbert then reads the whole application through. The attorney settles what the data supports and what the business needs the patent to do. See how we work with start-ups and established pharma, or read how to read a biotech patent.

In practice

A new set of results needs protecting. Darwin drafts the claims with the attorney one decision at a time, then the specification, then the sequence listing. Gilbert reads the whole thing for inconsistencies and the attorney sorts them out before filing.

Cassandra: Due diligence and IP contract review

Cassandra works through the deal information with us, so the risks are ranked before anyone signs.

IP sits at the heart of most biotech deals, and the diligence nearly always arrives with too little time attached. Cassandra keeps a single record of every fact, where it came from and how far it can be trusted, which leaves our attorneys free to spend the time on judgement rather than bookkeeping.

  • Intake: the deal brief, then the data, worked through across product identity and the patent portfolio to ownership, key parties and agreements
  • Analysis: coverage of the product claim by claim and country by country, validity from priority through to the data behind the claims, and the chain of title traced step by step
  • Verdict: risks ranked by how serious they are, each with an owner, with the strength of the evidence graded separately from the size of the risk

Cassandra also reads the IP terms in commercial agreements and flags what the attorney should look at. 

In practice

A deal is on the way. Cassandra goes through the information with us, logging each fact with its source and building the family table, so our attorneys can test coverage, validity and ownership claim by claim and have the risks ranked before signing.

Gilbert: Quality enhancement

Gilbert gives every draft and every response a second read against the law, the science and your instructions, and grades what it finds.

Patent documents are long, repetitive and unforgiving. One inconsistency between the claims and the description, or a sequence that does not quite match the lead, can sink a patent years later. Gilbert is our second or third pair of eyes before anything goes out:

  • Specification QE: inconsistencies, omissions and drafting slips across claims, description and figures
  • Sequence and compound QE: whether the claims really cover the lead sequence, compound or Markush formula
  • Prosecution QE: the response checked against the law, the science, your instructions and the attorney’s own notes
  • IP strategy QE: the claims checked against the strategy we agreed for the family

Each issue is graded critical, high, medium or low and the attorney decides what to change. The result is fewer formalities objections, fewer unnecessary claim fees, and the odd sequence error caught before it reaches the register. Related reading: the unforgiving gold standard.

In practice

A response is ready to file. Gilbert reads it against the law, the science, your instructions and the attorney’s notes, and grades each issue from critical down to low. The attorney decides what to change.

Franklin: Invention spotting and publication review

Franklin reads what your scientists are about to publish, and what your competitors already have, so that nothing valuable slips out and nothing confidential does either.

In a pharma or biotech company, inventions tend to be made faster than anyone notices them, and the next abstract or manuscript is often the real filing deadline. Franklin is built for that gap between the lab and the patent department. It prepares:

  • Publication review: a draft paper or poster read against your pending cases and earlier disclosures, with new inventions and confidential material flagged
  • Invention spotting: new data and internal reports searched for inventions nobody has protected yet, each assessed for novelty, inventive step and support
  • Competitive landscaping: a competitor’s papers and filings read together and kept current as their programmes move

The attorney decides what to file, when, and what the paper should say. Related reading: IP strategy for cell therapy FAQs, and how we build invention capture into Fractional IP counsel.

In practice

A draft paper lands two weeks before submission. Franklin sets it against your pending cases and earlier disclosures, and the attorney reviews it with the risks already marked. The paper goes out on time. So does the filing.

Ammonites: Patent portfolio visualisation

Patent strategy in the pharma industry is complex, multi-layered and can be infamously difficult to communicate. We solved that problem with the invention of the ammonite chart. Ammonites show the patent estate, or a whole competitive field, as a single visualisation. Ammonites are our go-to for boards and investors, and CEO's love them.

A spreadsheet or a complex array of arrows and dotted lines will not tell your board or an investor a clear story about your patents strategy. We build highly customizable and adaptable ammonites to help us tell the story about the IP that we want to tell. We’ve found that once you start using the ammonite, you can’t go back. We use it for:

  • Board presentations and investor decks
  • Strategic planning and life-cycle management
  • Competitive analysis and landscape reviews
  • Due diligence, where the first question is usually how long the runway is
  • Internal R&D project and IP team meetings with our Fractional IP counsel clients

In practice

The board wants to understand the status of the patent portfolio before launch and agreeing to further investment in new indications for the product. They want to know: What patents do you have? When do they expire? What do they cover? When is Loss of exclusivity? How much patent term is left for each of the cases? What are the life cycle management versus core product filings? Are the patent pending or granted? How does patent expiry compare to regulatory exclusivity protection? All of this an more is communicated clearly on the ammonite. 

Security and professional standards

Our use of AI sits inside the same professional rules as everything else we do.

We are a regulated practice, bound by duties of confidentiality, competence and care, and those duties do not stop at the AI. In practice that means:

  • Enterprise-grade security
  • No AI model training on client data
  • No retention of your data
  • Confidentiality safeguards throughout
  • A qualified attorney reviews every output

You get the speed of AI with the accountability your investors and partners expect from a regulated firm of patent attorneys.

A traditional patent firm, a generic AI tool, or Evolve?

An honest comparison. Where the AI sits is what makes the difference.

A traditional patent firm

Good attorneys, but the AI is either absent or an off-the-shelf product bolted on afterwards. How much analysis you get is limited by how many attorney hours you can afford.

Generic off-the-shelf legal AI used in-house

Limited capabilities in pharma and biotech, slow to adapt to changes in practice, each new tools requires you to upskill your team on how to use the software.

Evolve Intellectual Property

Pharma patent attorneys who develop their own tools and use them daily. The same analysis we have always done, started earlier and finished faster, with a qualified attorney signing the advice and a regulated firm standing behind it.

FAQs

Do you sell your AI tools?

No. The tools are how we do our work, not something we sell. Every client benefits from them on their own cases, including Fractional IP clients.

Are you using an AI software wrapper provider?

No. Every AI patent product on the market sits on a model from an LLM lab, and a wrapper simply puts a third party between you and that model, with its own confidentiality terms, its own roadmap and its own price. We build directly on the frontier models under enterprise terms, nothing you send is kept or used for training, and our attorneys write the instructions and workflows themselves.

Who is accountable for the output?

A qualified patent attorney, every time. The tools do the groundwork. The analysis and the advice are the attorney’s, and you get the same professional duty of care as on any other piece of our work.

Can AI draft a patent application?

Our tools can draft claims and specification sections quickly, and we use them for exactly that. What they cannot do is decide what the data supports, what an examiner will accept or what the business needs from the patent. That is the attorney’s job, and every draft goes through one before it goes anywhere.

Is Evolve IP the cloud communications company?

No. Evolve Intellectual Property is a firm of UK and European patent attorneys in Cambridge working only in pharmaceuticals and biotechnology. The US company called Evolve IP has nothing to do with us.

Contact us

The whole profession is working out how to use AI, and we would rather share what we have learned than sit on it. If you are in-house and would like to hear what we do, what has worked and what has not, we are happy to have an informal chat.

We also write an AI in the patent industry newsletter, with practical notes on workflows, prompting and the tools we use. Subscribe, or get in touch and we will add you to the list.

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