PHARMACEUTICAL IP

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  • Offering
    • Evolve AI
    • Fractional IP counsel
    • Services
      • AI guidance
      • Competitive intelligence
      • Deals
      • Due diligence
      • Freedom to operate
      • IP strategy and communication
      • Oppositions and appeals
      • Patent drafting
      • Patent prosecution
      • Trade secrets
    • Technologies
      • Pharmaceuticals
      • Biologics
      • Cell & gene therapy
      • AI drug discovery
    • Our clients
      • Biotech
      • CROs and CMOs
      • Established pharma
      • International IP counsel
      • Investors
      • Start-ups
      • Universities
  • Fractional IP counsel
    • Biotech
    • CROs and CMOs
    • Established pharma
    • International IP counsel
    • Investors
    • Start-ups
    • Universities
  • Evolve AI
  • Technologies
    • Pharmaceuticals
      • Dosing regimens
      • Formulations
      • Life cycle management
      • New indications
      • Platform technologies
    • Biologics
      • Antibodies
      • Antibody-drug conjugates (ADCs)
      • T cell engagers (TCEs)
    • Cell & gene therapy
      • CAR-T cell therapies
      • Gene therapies
      • In vivo CAR-T
      • Lipid nanoparticles (LNPs)
      • Macrophages (CAR-M)
      • mRNA therapeutics
      • Regenerative cell therapies
    • AI drug discovery
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Trade secrets

Not every innovation should be patented. Manufacturing know-how, data, models and processes that cannot be seen in the finished product are often better protected as trade secrets, if they are identified, documented and actively kept secret. At Evolve, we help pharma and biotech companies decide what to patent and what to keep secret, and build the processes that make trade secrets defensible.

Patent or trade secret?

A patent gives a strong but time-limited right in exchange for disclosure. A trade secret can last indefinitely, but gives no protection against independent development or reverse engineering. Process patents can be designed around, become obsolete as the process changes and are hard to enforce, because infringement cannot be seen in the finished product (Evolve Insights). Early manufacturing innovation is often better held as a trade secret, while features a competitor could reach independently are usually worth patenting. Most companies need a hybrid strategy (Evolve Insights).

Data, models and platforms

For AI drug discovery and other data-driven companies, datasets, trained models and know-how can be the most valuable assets, and are usually best protected by confidentiality and contract (Evolve Insights). Our understanding of the value of data is also changing quickly (Evolve Insights). Read more about our work on platform technologies.

Making trade secrets defensible

Trade secrets are protected under the Defend Trade Secrets Act in the US, under national laws implementing the Trade Secrets Directive in Europe, and under their own regimes in other major markets. Everywhere, protection depends on identifying the secret and taking reasonable steps to keep it. We help you build trade secret registers, access controls and know-how disclosure processes, and the employee, supplier and collaboration agreements that support them.

Trade secrets in disputes and deals

Trade secret claims now sit alongside patent litigation in pharma and biotech, as the claim brought by Arcturus against AbbVie over Capstan’s LNP technology shows (Evolve Insights). In deals, buyers test whether know-how is documented and really kept secret. We help you manage the risk on both sides of the table.

Fractional IP counsel

Our fractional IP counsel model places a named senior patent attorney inside your team as your head of IP, deciding with your scientists and leadership what to patent and what to keep secret, and keeping the trade secret programme running day to day.

Why fractional IP counsel for trade secrets? A trade secret programme only works if it is part of daily life in the lab and the plant. Our patent directors have managed know-how inside pharma and biotech companies, so they bring the real-world industry experience that you only get working in-house to deciding what to patent and what to keep secret. With our team covering patents, contracts and disputes, and Franklin reviewing publications before they go out, you get more than a traditional IP firm or a consultant with a template policy can offer, delivered with a global strategic approach.

Fractional IP counsel

Contact us today to discuss how to protect your know-how.

Evolve AI

Franklin: Invention spotting and publication review

Franklin reads what your scientists are about to publish, and what your competitors already have, so that nothing valuable slips out and nothing confidential does either.

In a pharma or biotech company, inventions tend to be made faster than anyone notices them, and the next abstract or manuscript is often the real filing deadline. Franklin is built for that gap between the lab and the patent department. It prepares:

  • Publication review: a draft paper or poster read against your pending cases and earlier disclosures, with new inventions and confidential material flagged
  • Invention spotting: new data and internal reports searched for inventions nobody has protected yet, each assessed for novelty, inventive step and support
  • Competitive landscaping: a competitor’s papers and filings read together and kept current as their programmes move

The attorney decides what to file, when, and what the paper should say. Related reading: IP strategy for cell therapy FAQs, and how we build invention capture into Fractional IP counsel.

More about Franklin
Franklin

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Row of gold panels with one turquoise panel inserted on dark blue, Evolve gene therapies image
Row of gold panels with one turquoise panel inserted on dark blue, Evolve gene therapies image

Navigating the complex LNP IP landscape

  • 1st July 2026
It is difficult to find a field of patent law in pharma and biotech at the moment that is more complicated and fast-moving than the field of lipid nanoparticles (LNPs). IP strategy for LNPs involves sophisticated science, multiple and overlapping technology platforms, trade secret and ownership disputes and global patent cross-litigation.
Single cut gold stone glowing turquoise at its heart on dark blue, Evolve abstract article image
Single cut gold stone glowing turquoise at its heart on dark blue, Evolve abstract article image

From oil to gemstones: Our shifting understanding of the value of data

  • 10th October 2025
The concept of data as oil has been around for a number of years, but does the analogy still hold? In the pharma and biotech industry, there is now a shift away from thinking of data as a bulk commodity of raw material, towards the pursuit of high quality data that can improve the performance…
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image

The problem with product-by-process patents (T 1065/23)

  • 18th July 2025
Inventions may be defined in a patent as product, a process, or a product defined by the process that it is made. The choice of patent claim format you choose to define the invention can be highly influential to validity and enforcement later on.
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image

Pitfalls of cell therapy manufacturing IP – A case study (T 0868/23)

  • 8th July 2025
In cell therapy the industry mantra is that the product is the process. However, this case illustrates that the best patent protection for a cell therapy is derived from the product. 
Grid of gold cubes with one turquoise cube lifted on dark blue, Evolve AI drug discovery image
Grid of gold cubes with one turquoise cube lifted on dark blue, Evolve AI drug discovery image

IP strategy for AI-assisted drug discovery

  • 29th April 2025
AI has been hailed as a potentially revolutionary tool for accelerating and enhancing the difficult and expensive process of drug discovery. Medicine perhaps represents the field in which AI has the most to offer humanity. However, the nascent field of AI-assisted drug design also highlights the need for IP strategy to be as forward-looking and…
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image
Flight of gold steps with one turquoise glowing step on dark blue, Evolve abstract article image

Beyond the process: Securing robust IP protection for cell therapies

  • 29th April 2025
Cell therapy represents one of the most exciting fields of innovation, with the potential to provide long-term cures for previously incurable diseases. However, unlike traditional pharmaceuticals, these “living medicines” present unique IP challenges that can make or break a biotech’s future.
Gold ball-and-stick molecule with one turquoise atom on dark blue, Evolve pharmaceuticals image
Gold ball-and-stick molecule with one turquoise atom on dark blue, Evolve pharmaceuticals image

The benefits and pitfalls of drug manufacturing IP (T 2543/22)

  • 23rd February 2025
Originally posted on IPKat. The Board of Appeal decision in T 2543/22 relates to a manufacturing method for preparing a therapeutic peptide. The Board of Appeal found that whilst various methods were known, the skilled person would not have had a reasonable expectation of success in applying them to produce the specific claimed peptide. The case highlights some…
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